Dr. Lucia Caceres

Instructor

LusciaCaceres

Email: Lucia.Caceres@dal.ca
Mailing Address: 
Dalhousie University Life Sciences Centre Room 1355 Oxford Street P.O Box 15000 Halifax, Nova Scotia B3H 4R2
 
Research Topics:
  • Developmental Neuroscience
  • Neuro-glial communication
  • Cellular mechanisms
  • Neuromuscular functions
  • Vertebrate and invertebrate neurobiology

Education

BSc in Biology with Specialization in molecular genetics (University of Alberta)
PhD Molecular Biology and Genetics (McGill University)

Teaching

Developmental neurobiology (NESC/PSYO 3270)
Genes, Brain, and Behaviour (NESC/PSYO 3670)
Behavioural Neuroscience (NESC/PSYO 3770)
Molecular Neuroscience (NESC/PSYO 3970)
Directed Reading Project (NESC/PSYO 4000)
Topics in Neuroscience (NESC/PSYO 4008)
Behavioural Neuro(epi)genetics and Genomics (NESC 4670)
Principles of Neuroscience: Systems and Behavioral Neuroscience (NESC 6102)
Cell Biology II (BIOL3420) and Cell Biology II lab (BIOL3420L)
Cell Biology I (BIOL-2321) and Cell Biology I Lab (BIOL2123L)
Genetics Laboratory (BIOL 2307)

Publications

  • Prykhozhij, S., Cáceres, L., Ban, Kevin, Cordeiro-Santanach, A., Kanneboyina, N Hoffman, E., Berman, J. N (2023). Loss of caplapin3b in Zebrafish, A model of limb-girdle muscular dystrophy, increases susceptibility to muscle defects due to elevated muscle activity. Genes 2023, 14, 492. https://doi.org/10.3390/genes1402049.
  • Prykhozhij, S., Cáceres, L., Kevin Ban, McMaster, C., M., Robitaille, J., Jason N. Berman (2021). Blood 138 (1): 2071. Loss of iqgap1 (IQ Motif Containing GTPase Activating Protein 1) in Zebrafish Leads to Intracerebellar Hemorrhage, Morphological Abnormalities and Activates Hematopoietic Response.
  • Prykhozhij, S., Cordeiro-Santanach, A., Cáceres, L., Jason N. Berman (2020). Genome editing in zebrafish using high-fidelity Cas9 nucleases. Methods Mol Biol 2115: 385-405. doi: 10.1007/978-1-0716-0290-4_21.
  • Cáceres, L., Prykhozhij S.V., Gjerde, H., Duff, N.M., Ngo, M., Cairns, E., Nasrallah, G., McMaster, C., Litvak, M., Robitaille, J., Berman, J.N (2019). Frizzled 4 regulates ventral blood vessel remodeling in the zebrafish retina. Developmental Dynamics 248(12): 1243-1256. doi: 10.1002/dvdy.117.
  • Borycz, Janusz., Ziegler, Anna., Borycz, A. Jolanta., Uhlenbrock Guido., Tapken, Daniel., Cáceres, Lucia., Hollmann, Michael., Hovemann, T. Bernhard., and Meinertzhagen, A. Ian (2018). Location and functions of Inebriated in the Drosophila eye. Biology Open 7: bio034926. doi:10.1242/bio.034926
  • Prykhozhij S.V., Cáceres L., Berman J.N (2017). New Developments in CRISPR/Cas-based Functional Genomics and their implications for Research using Zebrafish. Curr Gene Ther. 17(4): 286-300. doi: 10.2174/1566523217666171121164132.
  • Cáceres, L., Nećakov, A.S., Schwartz, C., Kimber, S., Roberts, I.J., Krause, H.M. (2011). Nitric oxide coordinates metabolism, growth, and development via the Nuclear Receptor E75. Genes & Development 25(14): 1476-85. Reviewed in: Nitric oxide directly regulates gene expression during Drosophila development: need some gas to drive into metamorphosis? (2011). Yamanaka N, O'Connor MB. Genes & Development 25(14):1459-63.
  • Cáceres, L., Nilson, L.A. (2009).  Translational repression of gurken mRNA in the Drosophila oocyte requires the hnRNP Squid in the nurse cells. Developmental Biology 326(2): 327-34.
  • Lécuyer, E., Nećakov, A.S., Cáceres, L., Krause, H.M., (2008). High-resolution fluorescent in situ hybridization of Drosophila embryos and tissues. CSH Protocols 3.
  • E.A. Silva, B.J. Lee, L.S. Cáceres, D. Renouf, B.R. Vilay, O. Yu, J.A. Bradley, and S.D. Campbell (2006).  A novel strategy for identifying mutations that sensitize Drosophila eye development to caffeine and hydroxyurea.  Genome 49: 1416-1427.
  • Cáceres, L. and Nilson, L.A. (2005). Production of gurken in the nurse cells is sufficient for axial patterning in the Drosophila oocyte. Development 132: 2345-2353. Cited by the Faculty of 1000: evaluations for Cáceres L & Nilson LA  Development 2005 Apr 13: http://www.f1000biology.com/article/15829517/evaluation. Reviewed in: Gurken activity in nurse cells polarizes Drosophila oocytes. (2005). Reprod Biomed Online 10:712.