Tamara Franklin

Assistant Professor


Email: Tamara.Franklin@dal.ca
Phone: 902-494-2923
Fax: 902-494-6585
Mailing Address: 
Dalhousie University, Life Sciences Centre, 1355 Oxford Street, P.O. Box 15000, Halifax, NS B3H 4R2
 
Research Topics:
  • Neuroscience
  • Epigenetics
  • In vivo electrophysiology
  • Animal behaviour
  • Neuroconnectivity
  • Sociability

 

Education

BSc (University of King’s College)
MSc (Dalhousie University)
PhD (Swiss Federal Institute of Technology (ETHZ))

Research Interests

I would like to understand the brain functions required to engage in normal peer-to-peer social interactions. For this, my laboratory uses a combination of epigenetic and neuroconnectivity approaches to (1) identify neural circuits required for appropriate social engagement, and (2) understand how epigenetic regulation affects functional connectivity within these circuits. Our research is relevant for social-related disorders like autism spectrum disorder and social anxiety disorder.

Selected Publications

  • Kosel FTorres Munoz P, Yang JR, Wong AA, Franklin, TB (2019). Age-related changes in social behaviours in the 5xFAD mouse model of Alzheimer's disease. Behavioural Brain Research. 362, 160-72. Doi: 10.1016/j.bbr.2019.01.029. Associated Dataset: "Social behaviours in the 5xFAD mouse" https://dx.doi.org/10.20383/101.0126.  
  • van Steenwyk G, Roszkowski M, Manuella F, Franklin TB, Mansuy IM (2018). Transgenerational inheritance of behavioral and metabolic effects of traumatic experiences in early postnatal life in mice: Evidence in the 4th generation. Environmental Epigenetics. 4, dvy023. Doi: 10.1093/eep/dvy023
  • Franklin TB, Silva BA, Perova Z, Marrone L, Masferrer ME, Zhan Y, Kaplan A, Greetham L, Verrechia V, Halman A, Pagella S, Vyssotski AL, Illarionova A, Grinevich V, Branco T, Gross CT (2017). Prefrontal cortical control of a brainstem social behavior circuit. Nature Neuroscience. 20, 260-70.  Doi: 10.1038/nn.4470
  • Gapp K, Soldado-Magraner S, Alvarez-Sanchez M, Bohacek J, Vernaz G, Shu H, Franklin TB, Wolfer, D., Mansuy, I.M. (2014). Early life stress in fathers improves behavioral flexibility in their offspring. Nature Communications. 5, 5466. Doi: 10.1038/ncomms6466.

Teaching

PSYO/NESC 7100
PSYO/NESC 3775