- In vivo electrophysiology
- Animal behaviour
BSc (University of King’s College)
MSc (Dalhousie University)
PhD (Swiss Federal Institute of Technology (ETHZ))
I would like to understand the brain functions required to engage in normal peer-to-peer social interactions. For this, my laboratory uses a combination of epigenetic and neuroconnectivity approaches to (1) identify neural circuits required for appropriate social engagement, and (2) understand how epigenetic regulation affects functional connectivity within these circuits. Our research is relevant for social-related disorders like autism spectrum disorder and social anxiety disorder.
- Franklin, T.B., Saab, B.J., Mansuy, I.M. (2012) Neural mechanisms of stress resilience and vulnerability. Neuron. 75:747-61. Doi: 10.1016/j.neuron.2012.08.016.
- Franklin, T.B., Linder, N., Russig, H., Thony, B., Mansuy, I.M. (2011). Influence of early stress on social abilities and serotonergic functions across generations. Plos One. 6:e21842. doi: 10.1371/journal.pone.0021842.
- Franklin, T.B., Weiss, I.C., Vizi, S., Mansuy, I.M. (2011) Inheritable effect of unpredictable maternal separation on behavioural responses in mice. Frontiers in Behavioural Neuroscience. 5:3. Doi: 10.3389/fnbeh.2011.00003.eCollection.2011.
- Franklin, T.B., Mansuy, I.M. (2010) Epigenetic inheritance in mammals: evidence for the impact of adverse environmental effects. Neurobiology of Disease. 39:61-5. doi: 10.1016/j.nbd.2009.11.012.
- Franklin, T.B., Russig, H., Weiss, I.C., Graff, J., Linder, N., Michalon, A., Vizi, S., Mansuy, I.M. (2010) Epigenetic transmission of the impact of early stress across generations. Biological Psychiatry. 68:408-15. doi: 10.1016/j.biopsych.2010.05.036.