List of Publications
Phone: (902) 494-3944
Fax: (902) 494-6585
- Vision impairment
- Cellular mechanisms
PhD (McMaster University)
PDF (Harvard Medical School)
Professor Duffy’s research aims to understand the neural events that permit sensory experience to shape brain development and function. His lab investigates cellular mechanisms that promote recovery from a vision impairment (amblyopia) caused by abnormal visual experience early in postnatal life.
•Lingley AJ, Bowdridge JC, Farivar R, Duffy KR (2018) Mapping of neuron soma size as an effective approach to delineate differences between neural populations. Journal of Neuroscience Methods 304, 126-135.
•Duffy KR, Fong, MF, Mitchell DE, Bear MF (2018) Recovery from the anatomical effects of long-term monocular deprivation in cat lateral geniculate nucleus. Journal of Comparative Neurology 526, 310-323.
•Fong MF, Mitchell DE, Duffy KR, Bear MF (2016) Retinal inactivation promotes recovery from amblyopia. Proceedings of the National Academy of Sciences 213, 14139-14144.
•Duffy KR, Lingley AJ, Holman KD, Mitchell DE (2016) Susceptibility to monocular deprivation following immersion in darkness either late into or beyond the critical period. Journal of Comparative Neurology, 524, 2643-2653.
•Mitchell DE, MacNeil K, Crowder NA, Holman K & Duffy KR (2015) Recovery of visual functions in amblyopic animals following brief exposure to total darkness. Journal of Physiology 594, 149-167.
•Song S, Mitchell DE, Crowder NA & Duffy KR (2015) Postnatal accumulation of intermediate filaments in the cat and human primary visual cortex. Journal of Comparative Neurology 523, 2111-2126. •Mitchell DE, Crowder NA, Holman K, Smithen M & Duffy KR (2015) Ten days of darkness causes temporary blindness during an early critical period in felines. Proceeding of the Royal Society 282 (1803).
•Mitchell DE & Duffy KR (2014) The case from animal studies for balanced binocular treatment strategies for human amblyopia. Ophthalmic Physiology 34, 129-145.
•Duffy KR & Mitchell DE (2013) Darkness alters maturation of visual cortex and promotes fast recovery from monocular deprivation. Current Biology, 23:382-386.
•O’Leary TP, Kutcher MR, Mitchell DE & Duffy KR (2012) Recovery of neurofilament following early monocular deprivation. Frontiers in Systems Neuroscience 6:22.