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Alan A. Doucette

Professor

doucette_alan

Related information

Department of Chemistry

Email: alan.doucette@dal.ca
Phone: 902-494-3714
Mailing Address: 
Department of Chemistry
Dalhousie University
6274 Coburg Road
P.O. Box 15000
Halifax NS B3H 4R2
 
Research Topics:
  • Analytical chemistry
  • Biological chemistry
  • Proteomics
  • Mass spectrometry
  • Separations


Education

  • BSc, Dalhousie University
  • PhD, University of Alberta
  • PDF, University of Alberta

Research interests

My research is in the area of biological mass spectrometry, with emphasis on the development of innovative technologies for improved characterization of complex protein mixtures. Our technologies lead to improved understanding of disease and enable the drug discovery process.

Selected awards and honours

  • Canadian Society for Chemistry Fred Beamish Award, 2012
  • Innovacorp I-3 Technology Start-Up Competition, Zone 2, 2nd place, 2012
  • Harry Shirreff Prize for Excellence in Research in Chemistry, 2010-2012

Selected publications

  • “Implications of partial tryptic digestion in organic-aqueous solvent systems for bottom-up proteome analysis.” M. J. Wall, G. H. Carey, G. A. Simms, F. Liu, and Alan. A. Doucette* (Anal. Chim. Acta., 2011. 703, 194-203).
  • “Top-Down and Bottom-Up Proteomics of SDS-Containing Solutions Following Mass-Based Separation.” D. Botelho, M. J. Wall, D. B. Vieira, S. Fitzsimmons, F. Liu, and Alan. A. Doucette* (J. Proteome Res., 2010, 9, 2863–2870).
  • “Multiplexed size separation of intact proteins in solution phase for mass spectrometry.” J. C. Tran and Alan. A. Doucette* (Anal. Chem., 2009, 81, 6201 – 6209).
  • “Rapid & effective focusing in a carrier ampholyte solution isoelectric focusing system: A proteome prefractionation tool.” J. C. Tran and Alan. A. Doucette* (J. Proteome Res., 2008, 7, 1761-1766).
  • “Gel-eluted liquid fraction entrapment electrophoresis: An electrophoretic method for broad molecular weight range proteome separation.” J. C. Tran and Alan. A. Doucette* (Anal. Chem., 2008, 80, 1568-1573).