Fall 2022 Research Update

Introduction by Dr Cheryl Kozey, Research Coordinator

Our faculty work tenaciously to advance their research - which makes recognition of their efforts so well-deserved. In this PT Matters issue we are highlighting Dr Scott Kehler's research - which involves frailty management and addresses the complexities of age.

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“One in five Canadians has lung disease. COPD (Chronic Obstructive Pulmonary Disease) is the number one reason for hospitalization in Canada. And at least 13% of our children live with asthma.”* Those figures are disturbing figures, which makes respiratory research so important.

Dr. Kehler’s research involves frailty management to address the complexities of aging. Scott believes that knowing patient frailty levels could have a significant impact in the delivery of prevention and rehabilitation programming, and that understanding frailty could guide healthcare decision-making to tailor or provide more intensive therapy so that those who are in the worst health can benefit.

Research Summary

While people with Chronic Obstructive Pulmonary Disease (COPD) are living
longer, it does not mean they are living in better health. Measuring frailty can determine the overall health of a person including those with COPD. Frailty is a state of reduced function and health. People with more health problems are frailer. Studies show that people with COPD are frailer than people without COPD. This is a problem because frailty in COPD is related to worse quality of life, more COPD disease flare-ups, reduced physical fitness and activity, and a greater risk of dying.

Even though frailty is common in COPD, it is not known how frailty changes over time in people with COPD compared to people without COPD. This project will track changes in frailty, called frailty trajectories, using data from a large population-based study, called CanCOLD. CanCOLD that includes adults from across Canada with and without COPD who have been followed for more than a decade. This project will also study whether physical fitness and activity are affected by how quickly frailty develops, because these factors can influence long-term health outcomes.

The project will determine if COPD exacerbations and their burden of COPD symptoms impact their frailty trajectory. The results from this research study are important because they could improve how resources are used for the delivery of healthcare to patients who need it the most, as part of their treatment or prevention of COPD. If this study is successful, then future research could identify if it is important and feasible to measure frailty as a part of COPD prevention and treatment.**

More recently Dr Kehler was awarded a CIHR Team grant led by Danielle Bouchard (Nominated Principal Applicant from NB), with Scott as the Early Career Researcher Principal Applicant and NS Lead. It is a 6-year grant worth $3 M. The grant title is: Understanding how to Attract, Adapt, Implement and Sustain an evidence-informed fall prevention exercise program in Community Settings: The AAIMS project. More to come on this project!

Well done Scott, we all wish you great success with this most important research.

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