Research efforts in the Stradiotto group are directed toward developing new classes of ancillary ligands/transition metal complexes that exhibit interesting and unusual reactivity patterns, with the goal of incorporating such reactivity into synthetically useful catalytic substrate transformations that can be employed by end-users in both academic and industrial settings.
Our current research program is focused on the development of:
- Highly effective ancillary ligands for use in challenging late metal-catalyzed cross-couplings and related substrate transformations, including multi-component reactions and hydroaminations.
- Earth-abundant first-row metal catalysts, toward the development of more sustainable and environmentally friendly chemical syntheses.
Central themes that link these various programs include: the establishment of innovative ligation strategies for use in constructing suitably reactive transition metal complexes; the evaluation of structure-activity relationships including mechanistic studies to guide the development of increasingly reactive complexes; and the development of new and synthetically useful substrate transformations.
Visit our publications section for a recent account of the projects ongoing in the group.