Our invited Perspective article summarizing our DalPhos/Ni chemistry to date entitled "The Development of Cage Phosphine ‘DalPhos’ Ligands to Enable Nickel-Catalyzed Cross-Couplings of (Hetero)aryl Electrophiles" is accepted to Chemical Science.
Nick successfully defends his PhD - well done and congrats!
March 2024
Our paper entitled "Thermal Nickel-Catalyzed N‑Arylation of NH-Sulfoximines with (Hetero)aryl Chlorides Enabled by PhPAd-DalPhos Ligation" appears in Organic Letters. Well done Sam, Peter, and Mike!
February 2024
Our paper entitled "DalPhos on Demand: Facile Ligand Generation Enables New Ligand Discovery and Expedient Catalyst Screening" appears in ACS Catalysis. Well done Josh and team!
January 2024
Our paper entitled "Ligand-Enabled Nickel Catalysis for the O‑Arylation of Alcohols and Phenols with (Hetero)aryl Chlorides Using a Soluble Organic Base" appears in ACS Catalysis. Well done Kathleen, Nick, and the rest of the team!
December 2023
Kathleen successfully defends her PhD - well done and congrats!
November 2023
Our collaborative invited paper entitled "Nickel-Catalyzed O-Arylation of Primary or Secondary Aliphatic Alcohols with (Hetero)aryl Chlorides: A Comparison of Ni(I) and Ni(II) Pre-catalysts" is accepted to the Journal of Organic Chemistry as part of the special issue on "Next-Generation Cross-Coupling Chemistry". Congrats Kathleen!
Mark gives an invited lecture at St. Francis Xavier University.
October 2023
Our paper entitled "DalPhos/Nickel-Catalyzed C2−H Arylation of 1,3-Azoles Using a Dual-Base System" appears in Organic Letters. Congrats to Nick!
Mark gives an invited lecture at the University of New Brunswick.
September 2023
Our paper entitled "Probing the Impact of Added Al(OTf)3 on DalPhos-Nickel Catalyzed N-Arylations of Amides with (Hetero)aryl Chlorides" appears in the European Journal of Organic Chemistry. Congrats to Mike!
August 2023
Mark gives an invited lecture at the Dalhousie University Clean Technology Research Institute.
Our collaborative paper (with Paraza Pharma) entitled "Nickel-Catalyzed N-Arylation of Optically Pure Amino Acid Esters with Activated (Hetero)aryl Electrophiles" appears in Organometallics. Congrats to Connor and team!
July 2023
Mark and Nick each present at the OMCOS conference in Vancouver.
Our review entitled "Advances in Nickel-Catalyzed O-Arylation of Aliphatic Alcohols and Phenols with (Hetero)aryl Electrophiles" appears in Synthesis. Congrats to Kathleen!
June 2023
Our collaborative paper (with Merck) entitled "Nickel-Catalyzed Chemoselective Arylation of Amino Alcohols" appears in Angewandte Chemie. Congrats to Kathleen!
Our collaborative paper (with Bayer AG) entitled "Palladium-Catalyzed Chemoselective Mono-alpha-Arylation of O-Protected Hydroxyacetone: Efficient Access to a High-Value Synthetic Intermediate" appears in Advanced Synthesis & Catalysis. Congrats to Josh and Travis!
May 2023
Mark win's the Canadian Governor General's Innovation Award! Links to the associated media interviews can be found on the front "Stradiotto Research Group" page.
Mark participates as a keynote speaker in the Thieme WebCheminar#14: Modern Nickel-Catalyzed Reactions
