Heather Fennell - Al Sayed
BSc, OC(C), COMT, MSc; Assistant Professor

Email: heather.fennell@iwk.nshealth.ca
Phone: (902) 470-7511
Mailing Address:
5850 University Avenue, 6th Floor
P.O.Box 9700, Halifax, NS
B3K 6R8
Research Interests
Heather is interested in strabismus-induced cytoskeletal changes in the feline lateral geniculate nucleus (LGN). Based on past research, we know that the immature visual system is susceptible to change when influenced by abnormal visual experience (like monocular deprivation). Heather has investigated whether or not strabismus (a less drastic form of abnormal visual experience) could have similar impacts on LGN layers associated with the deviated eye. She found that there was a loss in neurofilament within layers of the LGN associated with the deviating eye, but no decrease in the cross-sectional area of the cells within that layer. This means that strabismus-induced restructuring of the neural connections may indeed involve a loss of neurofilament protein in order to promote neural pliancy within the visual system. In the future, we hope to explore the possible mechanisms by which this neurofilament protein is being broken down.